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Dominic W. Lai

Senior Medical Director at Seagen

Key strengths: Dominic approaches his work with clarity in thought, orthogonal thinking, and strategic planning. He has a bias towards action and enjoys supporting colleagues to improve their own performance. Professional biography: In the pharmaceutical industry, Dominic's initial focus was on early phase clinical development of oncology assets. He shepherded the clinical preparation for six IND submissions (ABBV-428, ABBV-927, ABBV-151, domvanalimab, AB680, and SGN-CD30C) and defined the expansion dose for 3 molecules (ABBV-085, ABBV-927, and domvanalimab). His work at MedImmune (2013-2015) included combination trials evaluating checkpoint inhibitors (durvalumab and tremelimumab) and angiogenic inhibitors in various solid tumors. At AbbVie (2015-2018) and at Arcus (2018-2019), he continued this focus and shepherded trials evaluating novel combinations of immunotherapies in solid tumors. Of note, these trials included intratumoral administration and trial designs informed by genomics. Now at Seagen (formerly known as Seattle Genetics), Dominic works in the late phase development group, working on projects evaluating brentuximab vedotin and enfortumab vedotin. One of the joys of working within industry for Dominic is working with colleagues of diverse backgrounds towards novel solutions. Personal Biography: Born in Hong Kong, Dominic immigrated to the US with his family at the tender age of seven. He moved many times during his childhood but his family ultimately settled in Los Angeles (which included a stint in East Los Angeles). Nurtured towards academic excellence by his parents, he studied molecular biology and creative writing at UC Berkeley, medicine at Albert Einstein College of Medicine, and medical oncology at NYU Langone Medical Center. He is board certified in internal medicine and medical oncology. While Dominic worked in private practice, his desire for macroscopic impact led him to join the pharmaceutical industry in 2013. Keywords: Clinical trials, clinical research, biomarker development, translational science, medical oncology, drug development, clinical development, immunotherapy, immuno-oncology, and business development.

Contact Information

Personal Email
d*****@gmail.com
Direct Phone
+1 62********
Location
South San Francisco, California

Company Information

Company
Headquarters
Founded Year
1998
Specialties
Antibody-Drug ConjugatesConjugation ChemistryMonoclonal antibody-based therapies for cancerCancer drug developmentDrug developmentBlood cancersBladder cancerHodgkin lymphomaNon-Hodgkin lymphoma

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View Colleagues

Harch Ooi
Harch Ooi

Associate Director - External Manufacturing Operations - Small Molecules (Europe)

Natalie Saint-Johnson
Natalie Saint-Johnson

Associate Director, Clinical Data Management

Evan Green
Evan Green

Research Associate III

Bill Gembala
Bill Gembala

Associate Director, Medical Writing

Karol Mayer
Karol Mayer

Senior Oncology Account Manager

Frequently Asked Questions Regarding Dominic W. Lai

What company does Dominic W. Lai work for?
Dominic W. Lai works for Seagen
What is Dominic W. Lai’s role in Seagen?

Dominic W. Lai's role in Seagen is Senior Medical Director

Who are Dominic W. Lai’s colleagues?

Dominic W. Lai's colleagues are Harch Ooi, Natalie Saint-Johnson, Evan Green, Bill Gembala, Karol Mayer.